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Philip W. Gold

Philip W. GoldScholars Council, 2004 - present
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Blog: “Depression: What It Is and How it Can Be Treated – A Conversation with Philip W. Gold”

PHILIP W. GOLD received his undergraduate and medical degrees at Duke University and his postgraduate medical training at the Harvard Medical School. He has been at the NIH Clinical Center since 1974, where he served as Chief of Neuroendocrine Research in the NIMH Intramural Research Program. Dr. Gold and his colleagues have pioneered in the elucidation of fundamental mechanisms of the neurobiology of the stress response and its dysregulation in major depression. He and his colleagues developed one of the first hypothesis-based treatments for depressive illness based on their work with corticotrophin-releasing hormone, which they first introduced to clinical medicine. He has also elucidated mechanisms of the premature coronary artery disease of major depression and first described the premature osteoporosis that occurs commonly in premenopausal women with depression. He is an author of more than 500 publications, including a series of nine full-length articles in the New England Journal of Medicine. Over 25,000 other scientific papers have cited his work. He has been honored on numerous occasions and has served on the MacArthur Foundation Medical Network.

Selected Publications

  • "Clinical and Biochemical Manifestations of Depression," The New England Journal of Medicine, 1988
  • "Acute Hypothalamic–Pituitary–Adrenal Responses to the Stress of Treadmill Exercise," The New England Journal of Medicine, 1987
  • "Responses to Corticotropin-Releasing Hormone in the Hypercortisolism of Depression and Cushing's Disease," The New England Journal of Medicine, 1986
  • "NIH Symposium on Mechanisms of Physical and Emotional Stress" (1986)

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